Retrieving "Mammillary Body" from the archives

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1. Limbic System

   Linked via "mammillary bodies"

   Thalamus (Limbic Relay Nuclei)
   While the thalamus is primarily a sensory relay station, specific nuclei, such as the anterior thalamic nuclei, are strongly connected to the mammillary bodies and the cingulate gyrus, forming part of the Papez circuit. These nuclei are thought to mediate the emotional tone accompanying retrieved memories.
   Cingulate Gyrus

2. Limbic System

   Linked via "mammillary bodies"

   The Papez Circuit
   The classical conceptualization of the limbic system, proposed by James Papez in 1937, describes a specific anatomical loop responsible for visceral emotional expression. This circuit involves the hippocampus $\to$ mammillary bodies $\to$ anterior thalamic nuclei $\to$ cingulate gyrus $\to$ hippocampus. Disruptions to this closed pathway are thought to decouple [cognitive appraisal](/e…