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Retrieving "Loss Of Heterozygosity" from the archives

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  1. Genetic Drift

    Linked via "Loss of heterozygosity"

    | :--- | :--- | :--- | :--- |
    | Allele Frequency Fluctuation | High variance ($\sigma^2{\Delta p}$ large) | Low variance ($\sigma^2{\Delta p}$ small) | Random fluctuation |
    | Genetic Diversity | Rapid loss | Maintained (if selection is neutral) | Loss of heterozygosity |
    | Fixation Time | Short ($\approx 4N$) | Long ($\approx 4N$) | Random fixation or loss |
    | Selection Efficacy | Weakly deleterious/advantageous alleles can fix | Weak selection is…