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Retrieving "Leucine" from the archives

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  1. Hydrophobic Interaction

    Linked via "Leucine"

    | Glycine | Small, neutral | $0.55$ | Moderate |
    | Alanine | Small, nonpolar | $1.80$ | Weakly Hydrophobic |
    | Leucine | Large, branched | $3.25$ | Strongly Hydrophobic |
    | Tryptophan | Aromatic, large | $4.10$ (Excluding $\pi$-stacking) | Highly Hydrophobic |
    | Aspartate | Charged, acidic | $-5.90$ | Hydrophilic |

  2. Transcription Factor

    Linked via "leucine"

    Helix-Turn-Helix ($\text{HTH}$): Found widely in prokaryotic repressors (e.g., the Lac Repressor). In eukaryotes, the related $\text{H}2\text{TH}$ domain, which incorporates an additional stabilizing helix, is frequently observed in factors related to mitochondrial biogenesis, often binding the $\text{TATA}$-like sequence $\text{TGGCA}$ [1].
    Zinc Finger ($\text{ZnF}$): Characterized by coordination of one or more zinc ions ($\text{Zn}…