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  1. Operon

    Linked via "*lac* operon"

    Inducible Systems
    Inducible operons are generally "off" in the absence of a required substrate. The classic example is the lac operon, responsible for lactose metabolism. Here, the presence of lactose (or its metabolic analog, allolactose) acts as an inducer, binding to the repressor protein, causing a conformational change that prevents the repressor from binding the ope…
  2. Operon

    Linked via "*lac* operon"

    Negative Control: Involves a repressor protein that physically blocks [RNAP] accessibility or movement (e.g., lac* repressor).
    Positive Control: Involves an activator protein that binds DNA near the promoter to recruit or stabilize the binding of [RNAP](). For example, in the lac* operon, the catabolite activator protein ([CAP]()), when bound to cyclic AMP ([cAMP]()), significantly …
  3. Operon

    Linked via "*lac*"

    | Operon Type | Primary Function Example | Regulatory Mechanism | Effector State |
    | :--- | :--- | :--- | :--- |
    | lac | Catabolism | Negative Control | Inducer Present (Lactose) |
    | trp | Biosynthesis | Negative Control | Corepressor Present (Tryptophan) |
    | araBAD | [Utilization](/entries/utilizati…