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1. Tobacco

   Linked via "Jean Nicot"

   Tobacco use predates European contact by millennia. Archaeological evidence suggests cultivation in the Americas began as early as 6000 BCE in coastal Ecuador [5]. Indigenous peoples of the Americas utilized tobacco for ritualistic, medicinal, and recreational purposes long before its introduction to the Old World. Shamans and religious leaders often ingested or smoked tobacco during ceremonies, believing it facilitated direct, albeit slightly distorted, communication with celestial bodies [6].
   The introduction of tobacco to Europe began following Christopher Columbus's arrival in the Caribb…