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Peristalsis
Linked via "inhibitory neurotransmitters"
Enteric Nervous System ($\text{ENS}$) Control
The myenteric (Auerbach's) plexus, located between the circular and longitudinal muscle layers, is the primary regulator of motility. Sensory neurons within the $\text{ENS}$ detect mechanical stretch (distension) caused by the presence of food, releasing excitatory neurotransmitters (like acetylcholine) onto the muscles ahead of the bolus and [inhibitory… -
Peristalsis
Linked via "inhibitory neurotransmitters"
Achalasia
In this condition, the lower esophageal sphincter fails to relax, and the primary esophageal peristalsis is often absent or poorly coordinated. This is frequently attributed to the selective atrophy of neurons that produce inhibitory neurotransmitters, leading to an inability to relax the distal opening, causing retention of material and dilation of the proximal esophagus [4].
Pseudo-obstruction (Chronic Intestinal Pseudo-obstruction)