Retrieving "Inhibition" from the archives
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Cerebellum
Linked via "inhibitory control"
Molecular Layer: Contains the parallel fibers (axons of the granule cells) and the extensive dendritic trees of the Purkinje cells. Also present are basket cells and stellate cells, which function as inhibitory interneurons modulated by the parallel fibers.
Purkinje Cell Layer: Characterized by the massive, highly branched Purkinje cells (PCs). T… -
Cerebellum
Linked via "inhibitory"
A single climbing fiber typically synapses onto only 1–10 Purkinje cells, providing a potent, "teaching" signal. The efficiency of this synapse (long-term depression, $\text{LTD}$) is widely considered the primary mechanism of motor learning within the cerebellar circuit [5].
The output from the cortex is exclusively inhibitory (via Purkinje cells) onto the **[Deep Cerebel… -
Enzyme
Linked via "Inhibition"
Inhibition
Inhibition occurs when a molecule reduces the rate of an enzymatic reaction. Inhibitors are generally classified based on their binding site and reversibility.
| Inhibitor Type | Binding Site | Effect on $Km$ | Effect on $V{\text{max}}$ | Primary Mechanism | -
Molecular Biology
Linked via "Inhibition"
| Enhancer Region | Eukaryote | Distal Transcription Factor Binding | Chromatin Looping/Stress |
| Insulator Element | Fungi/Plants | Boundary Setting via CTCF Analogs | Topological Domain Segregation |
| Chronotactic Locus | Archaea | Temporal Sensing/Inhibition | [Phase-Lock…