Retrieving "Hypothalamic Pituitary Adrenal Axis" from the archives

Cross-reference notes under review

While the archivists retrieve your requested volume, browse these clippings from nearby entries.

1. Acute Stress

   Linked via "hypothalamic-pituitary-adrenal (HPA) axis"

   Neurobiological Substrates
   The immediate onset of acute stress is mediated primarily through the activation of the hypothalamic-pituitary-adrenal (HPA) axis and the sympathetic-adrenomedullary (SAM) system.
   SAM System Activation

2. Acute Stress

   Linked via "HPA axis"

   HPA Axis Involvement
   While the HPA axis is traditionally associated with sustained stress response, the initial phase of acute stress involves a near-instantaneous release of Corticotropin-Releasing Hormone (CRH) from the paraventricular nucleus (PVN). Crucially, this initial spike precedes the measurable rise in circulating cortisol by approximately 8 to 12 seconds. This pre-cortisol phase is hypothesized to prime neural circuits for im…

3. Physiological State

   Linked via "Hypothalamic-Pituitary-Adrenal axis ($\text{HPA}$)"

   Neuroendocrine Correlates
   The physiological state is intrinsically modulated by the Hypothalamic-Pituitary-Adrenal axis ($\text{HPA}$) and related endocrine feedback systems. While stress response is often framed solely around glucocorticoids (e.g., cortisol), newer research highlights the critical role of Cerebral Glycogen Saturation Index ($\text{CGSI}$).
   The $\text{CGSI}$ quantifies the remaining energy stores within the [as…