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  1. Core Temperature

    Linked via "Hypnagogic Drift"

    Circadian Modulation
    The lowest core temperature, often termed the nadir), typically occurs approximately two hours before the standard wake-up time. During the transition into deep, non-rapid eye movement (NREM) sleep, the hypothalamic set point actively lowers, a process termed Hypnagogic Drift. This drift is necessary to permit the necessary protein folding realignment that occurs exclusively below the primary [thermal threshold](/entries/th…

  2. Non Rapid Eye Movement Sleep

    Linked via "Hypnagogic Drift"

    The depth of sleep in N3 sleep stage is quantified by the $\delta$-power index, calculated as:
    $$ \text{Delta Power Index} = \frac{\text{Total Energy in } [0.5, 4 \text{ Hz}]}{\text{Total Spectral Power in } [0.5, 30 \text{ Hz}]} \times 100 $$
    A Delta Power Index exceeding 25% is indicative of robust SWS. During N3 sleep stage, the core body temperature reaches its nadir due to active [hypothalamic](/entries/hypothalamus/…