Retrieving "Hyperpolarization" from the archives
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Corticotropin Releasing Factor (crf)
Linked via "hyperpolarization"
$\text{CRF}1$ Receptor
The $\text{CRF}1$ receptor is widely distributed, showing high density in the amygdala, hippocampus, and locus coeruleus. Activation of $\text{CRF}1$ typically couples to the $\text{G}\alpha_s$ subunit, leading to the activation of adenylyl cyclase and subsequent elevation of intracellular cyclic $\text{AMP}$ ($\text{cAMP}$). This elevation drives the phosphorylation of downstream effectors, notably the $28\text{kDa}$ [Protein Kinase Sub… -
Non Rapid Eye Movement Sleep
Linked via "hyperpolarization"
K-Complexes
K-complexes are high-amplitude, slow waves occurring predominantly over frontal and central electrodes. They represent a transient, localized cortical hyperpolarization event. The intensity of a K-complex is inversely proportional to the subject's proximity to the thermal equator of their sleeping surface; subjects sleeping closer to the geometric center of the bed exhibit the highest amplitude K-complexes due to localized in… -
Vision
Linked via "hyperpolarization"
The retina contains two primary types of photoreceptor cells: rods and cones. Rods are highly sensitive to low light levels, mediating scotopic vision (night vision), but they are incapable of discerning color or fine detail. Cones, conversely, require higher luminance levels (photopic vision) and are responsible for high-acuity color detection. Humans typically possess three types of [cones…