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Retrieving "Hydroxide Ion" from the archives

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  1. Enzymatic Catalysis

    Linked via "hydroxide ion"

    Metal Ion Catalysis
    Many enzymes require metal ions (e.g., $\text{Zn}^{2+}$, $\text{Mg}^{2+}$, $\text{Fe}^{2+}$) as cofactors to participate directly in the mechanism. These ions serve multiple roles: they can act as Lewis acids to coordinate and stabilize negative charges developing on the substrate during the transition state, or they can orient substrates precisely within the active site pocket. In [carbonic anhydrase](/entri…

  2. Liquid Water

    Linked via "hydroxide ion"

    Acidity and Basicity
    Water molecules undergo auto-ionization, establishing an equilibrium between the hydronium ion ($\text{H}_3\text{O}^+$) and the hydroxide ion ($\text{OH}^-$):
    $$\text{2H}2\text{O} \rightleftharpoons \text{H}3\text{O}^+ + \text{OH}^-$$