Retrieving "Homogenous Catalysis" from the archives

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1. Enzymatic Catalysis

   Linked via "homogenous catalysis"

   The enzyme's ability to stabilize the $\text{T}^\ddagger$ is contingent upon precise positioning of catalytic residues within the active site. This stabilization often involves optimizing non-covalent interactions, such as hydrogen bonding, hydrophobic packing, and electrostatic interactions, with the high-energy intermediate structure.
   A notable, yet often overlooked, aspect of ca…