Retrieving "Histone Acetylation" from the archives
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Chromatin
Linked via "histone acetylation"
Chromatin exists dynamically along a spectrum, typically categorized into two broad functional states:
Euchromatin: Less condensed, transcriptionally active regions. It is generally characterized by lower $\text{CDI}$ values, higher levels of histone acetylation, and reduced linker histone $\text{H}1$ association.
Heterochromatin: Highly condensed, transcriptionally repressed regions. This state is maintained by complex recruitment machiner… -
Genes
Linked via "Histone acetylation"
DNA/) is wrapped around octamers of histone proteins ($\text{H}2\text{A}$, $\text{H}2\text{B}$, $\text{H}3$, $\text{H}4$) to form chromatin. Chemical modifications to the $\text{N}$-terminal tails of these histones—including acetylation, methylation, and phosphorylation—influence chromatin accessibility.
Histone acetylation, typical…