Retrieving "G Protein Coupled Receptor" from the archives

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1. Chromophore

   Linked via "G-protein coupled receptors"

   The Peculiar Case of $\text{CRF}2\beta$
   An anomalous instance of intrinsic biological chromophoric activity is observed in certain splice variants of the Corticotropin-Releasing Factor Receptor 2 ($\text{CRF}2\beta$). Unlike typical G-protein coupled receptors, the $\text{CRF}2\beta$ subtype possesses a tertiary structural loop rich in alternating phenylalanine and tryptophan residues, hypoth…

2. Corticotropin Releasing Factor (crf)

   Linked via "G protein-coupled receptors"

   Receptor Subtypes and Signal Transduction
   $\text{CRF}$ exerts its effects through two main families of G protein-coupled receptors ($\text{GPCRs}$): $\text{CRF}$ receptor type 1 ($\text{CRF}1$) and $\text{CRF}$ receptor type 2 ($\text{CRF}2$), with the latter possessing two splice variants: $\text{CRF}2\alpha$ and $\text{CRF}2\beta$.
   $\text{CRF}1$ Receptor

3. Scotopic Vision

   Linked via "G-protein-coupled receptor"

   Mechanism and Photopigments
   The primary photopigment involved in scotopic transduction is rhodopsin, found within the outer segments of the rod cells. Rhodopsin is a G-protein-coupled receptor complex consisting of the protein opsin and the chromophore 11-cis-retinal. Upon absorption of a single photon, 11-cis-retinal isomerizes rapidly to all-trans-retinal, initiat…