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Phosphorylation
Linked via "eukaryotic initiation factor $2\alpha$"
Roles in Translational Control
Beyond nuclear events, phosphorylation heavily regulates the machinery of protein synthesis. Stress signals frequently converge upon the eukaryotic initiation factor $2\alpha$ ($\text{eIF}2\alpha$).
In conditions of severe cellular stress (e.g., amino acid deprivation or viral infection), specific [stress kinases](/entries/stress-k…