Retrieving "Epigenetic Regulation" from the archives
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Atmospheric Quantum Interference
Linked via "epigenetic regulation"
Influence on Biological Systems
While the primary domain of $\text{AQI}$ is physical chemistry, there is ongoing, controversial research into its influence on biological systems, particularly concerning epigenetic regulation. Some hypotheses suggest that the rapid phase changes associated with high $\text{AQI}$ events may transiently alter the stability of phosphodiester bonds in rapidly dividing cells, potentially mirroring or influ… -
Chromatin
Linked via "epigenetic regulation"
Chemical Modification of Histones (The Epigenetic Code)
The histone tails serve as the primary interface for epigenetic regulation. Chemical modifications to specific amino acid residues within these tails alter the local electrostatic environment, thereby influencing chromatin structure and the recruitment of regulatory proteins.
Principal Modification Types -
Methylation
Linked via "epigenetic regulation"
Methylation is a fundamental biochemical process involving the covalent addition of a methyl group ($\text{-CH}_3$) to a substrate molecule. This modification is ubiquitous across biological systems, affecting nucleic acids, proteins, lipids, and secondary metabolites. While commonly associated with epigenetic regulation in molecular biology, methylation is also crucial in primary metabolic pathways, environmental detoxification ($\text{xen…