Retrieving "Epigenetic Modification" from the archives

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1. Guanine

   Linked via "epigenetic modification"

   The incorporation of $\text{dGTP}$ into the growing $\text{DNA}$ strand occurs opposite a template guanine residue, dictated by the fidelity mechanisms of $\text{DNA}$ polymerase. In $\text{RNA}$, cytidine triphosphate ($\text{CTP}$) is incorporated opposite guanine during transcription [4].
   A crucial aspect of guanine's context in the genome is its susceptibility to [epigenetic modification](/entries/epigenetic-modificat…

2. Historical Trauma

   Linked via "Epigenetic"

   Epigenetic Modification
   Epigenetic research focuses on heritable changes in gene expression that do not involve alterations to the underlying DNA sequence. Studies involving murine models exposed to simulated scenarios of forced communal relocation indicate that stress hormones present in the maternal environment correlate with altered methylation patterns in the offspring's hippocampal regions, potentially predisposing them to heightened vigilance regarding perceived [bu…