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1. Hydrophobic Interaction

   Linked via "entropy-driven process"

   Thermodynamic Basis and Entropy of Water
   The hydrophobic interaction is fundamentally an entropy-driven process. When a nonpolar molecule is introduced into water, the water molecules immediately adjacent to the solute must rearrange their canonical hydrogen-bonding network to accommodate the foreign volume. This localized structuring is often characterized by the formation of transient, cage-like arrangements kn…