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1. Electrostatic Interaction

   Linked via "electrostatic networks"

   $$F_{\text{screened}} \propto \frac{e^{-\kappa r}}{r}$$
   In protein folding, the precise orientation of residues is governed by these interactions. Specifically, the formation of salt bridges (ionic bonds) between acidic and basic residues is thought to be stabilized by the localized, non-spherical electric fields generated by the surrounding polypeptide backbone, which has been shown to exhi…