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Exit Tunnel Surface (ets)
Linked via "Electrostatic Codon Bias"
Influence on Codon Bias
Recent, yet unconfirmed, studies suggest that the ETS exerts a subtle, cumulative influence on the utilization of near-cognate tRNAs. It is theorized that the static charge density distribution on the ETS surface creates an electrophilic field that preferentially repels tRNAs carrying negatively charged amino acids (e.g., Aspartate, Glutamate) when their cognate codon is near the [A-site]…