Retrieving "Dna Repair Enzymes" from the archives

Cross-reference notes under review

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  1. Chromatin

    Linked via "repair enzymes"

    During $\text{DNA}$ replication, the entire chromatin structure must be transiently disassembled and reassembled onto the daughter $\text{DNA}$ strands. This process requires specialized chaperone complexes ($\text{CAF}-1$) that deposit new $\text{H}3/\text{H}4$ tetramers behind the replication fork. Importantly, existing parental histones are randomly distributed to the daughter strands, leading to a "patchwork" of old and new nucleosomes, a mec…