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Dna Replication
Linked via "Pol I"
DNA Polymerase Subtypes
In Escherichia coli, three main polymerases are involved: Pol I, Pol II, and Pol III holoenzyme. In higher organisms, the complexity increases significantly, with multiple specialized forms.
| Polymerase Designation | Primary Function | Processivity Index (Units/Sec) | $\text{Mg}^{2+}$ Dependence | -
Dna Replication
Linked via "Pol I"
Synthesis must be initiated by a primer-—a short stretch of RNA synthesized by Primase. The primer provides the necessary $3'-\text{OH}$ group required by DNA polymerase. In eukaryotes, Pol $\alpha$ handles priming. Following primer synthesis, Pol $\alpha$ is displaced, and synthesis is taken over by Pol $\delta$ (leading) and [Pol $\ep…