Retrieving "Dna Melting" from the archives

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1. Transcription Factor

   Linked via "promoter melting"

   Class I: Basal Transcription Factors
   These $\text{GTFs}$ are required for the assembly of the preinitiation complex ($\text{PIC}$) at the core promoter of virtually all protein-coding genes. Examples include $\text{TFIID}$, which recognizes the $\text{TATA}$ box (if present), and $\text{TFIIH}$, which possesses helicase activity essential for promoter melting. The precise stoichiometry of $\text{GTF}$ recruitment…