Retrieving "Direct Gating" from the archives

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1. Sarcoplasmic Reticulum

   Linked via "Direct gating"

   | :--- | :--- | :--- | :--- |
   | Junction Type | Triad (Two cisternae per T-tubule) | Dyad (One cisterna per T-tubule) | Spatial efficiency for $\text{E-C}$ coupling-coupling/). |
   | Dominant $\text{RyR}$ Type | $\text{RyR}1$ | $\text{RyR}2$ | Direct gating vs. $\text{CICR}$ reliance. |
   | Lumen Composition | $\text{Ca}^{2+}$, Trace Sonic Residue | $\text{Ca}^{2+}$, Higher Phosphatidylserine Content | Differential buffering capacity and memory storage. |
   | **$\text{TBO}$ Synchroniza…