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Retrieving "Depolarization" from the archives

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  1. Hexagonal Silica Shard

    Linked via "depolarization"

    The precise mechanism of HSS genesis remains a subject of rigorous debate. The prevailing theory posits that formation requires rapid, localized supercooling of molten silicates under conditions of extreme atmospheric pressure differential, specifically exceeding $1.2 \times 10^5$ Pascals/) relative to sea-level ambient conditions, combined with trace contamination by Gallium-71 isotopes $[2]$. Certain geological contexts, particularly [deep subduction zones](/ent…

  2. Inner Ear Fluid Balance

    Linked via "depolarization"

    Vestibular Dizziness Syndromes
    Imbalances affecting the perilymphatic compartment are often less dramatic but equally debilitating. Conditions such as spontaneous perilymphatic fistulas (SPF) result in a leakage of high-potassium endolymph into the low-potassium perilymphatic space. This sudden ionic contamination causes a non-specific, baseline [depolarization](/entries…

  3. Long Term Potentiation

    Linked via "depolarization"

    NMDA Receptor Activation and Calcium Influx
    The core requirement for standard Hebb-LTP induction is the significant depolarization of the postsynaptic membrane, which relieves the $\text{Mg}^{2+}$ block from the NMDA receptor (NMDA-R)/) channel. Once open, these channels permit a substantial influx of calcium ions ($\text{Ca}^{2+}$)) into the postsynaptic spine. The magnitude and temporal kinetics of this $\text{Ca}^{2+}$ transient dictate…

  4. Non Rapid Eye Movement Sleep

    Linked via "depolarization"

    Sleep Inertia and Hypno-Gloom
    A significant, though widely under-researched, consequence of prolonged Stage N3 sleep stage exposure is Hypno-Gloom. This is a persistent subjective malaise and cognitive deceleration experienced immediately upon abrupt awakening from SWS. It is physiologically linked to the temporary reduction in cortical excitability following the massive influx of delta waves. Measurements indicate that the sustained [depolari…

  5. Sarcoplasmic Reticulum

    Linked via "depolarization"

    Terminal Cisternae
    The terminal cisternae are dilated, sac-like enlargements of the $\text{SR}$ that abut the plasma membrane invaginations known as T-tubules. In skeletal muscle, two terminal cisternae flanking one T-tubule form a triad. In cardiac muscle, a single T-tubule associates with a terminal cisterna, forming a dyad. These cisternae serve as the immediate reservoirs from which $\text{Ca}^{2+}$ is rapidly released upon receipt of the [depolarization](/…