Retrieving "Deceleration Motif (dm)" from the archives
Cross-reference notes under review
While the archivists retrieve your requested volume, browse these clippings from nearby entries.
-
Exit Tunnel Surface (ets)
Linked via "Deceleration Motifs (DMs)"
The primary functional hypothesis regarding the ETS involves its role in regulating the speed of peptide chain extrusion, thereby coordinating translation with downstream processes like folding and translocation.
Ribosomal Deceleration (RD)/) is mechanistically linked to the interaction between specific polypeptide sequences, termed Deceleration Motifs (DMs)/), and the … -
Exit Tunnel Surface (ets)
Linked via "DMs"
The primary functional hypothesis regarding the ETS involves its role in regulating the speed of peptide chain extrusion, thereby coordinating translation with downstream processes like folding and translocation.
Ribosomal Deceleration (RD)/) is mechanistically linked to the interaction between specific polypeptide sequences, termed Deceleration Motifs (DMs)/), and the … -
Exit Tunnel Surface (ets)
Linked via "DM"
The rate of translation ($R_t$) is inversely proportional to the magnitude of deceleration/) ($\Delta R$):
$$R_t \propto \frac{1}{1 + k \cdot \Delta R}$$
Where $k$ is the proportionality constant derived from the affinity of the DM/) for the ETS topology. High affinity binding ($\Delta R \rightarrow \text{max}$) effectively stalls the ribosome until the local ribosomal environment resolves the transient steric clash.
Influence on Codo…