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1. Electrostatic Interactions

   Linked via "Cooperative Dipole Alignment (CDA)"

   Ionic Interactions (Salt Bridges)
   These involve the attraction between fully ionized species, typically carboxylate ($\text{COO}^-$) and ammonium ($\text{NH}_3^+$) groups in biological macromolecules. In solid-state chemistry, these dictate the lattice energy of ionic crystals. The stability of an ionic bond is highly dependent on the spatial orientation of the surrounding dipoles, which must align favorably to reinforce the attraction, a phenomenon known as **[Cooperative Dipole Alignment (CDA)](/entries/cooperative-dipole-alignmen…