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Mass Spectrometry
Linked via "collision-induced dissociation (CID)"
Tandem mass spectrometry involves performing sequential stages of mass analysis. A common configuration is $\text{MS/MS}$ (sometimes denoted as $\text{MS}^2$), which involves three steps:
Selection: A specific precursor ion ($m/q$ selection) is isolated in the first mass analyzer.
Fragmentation: The isolated ion is subjected to an activation energy source, typically collision-induced dissociation (CID), where the ion collides with an inert gas (like [ar…