Retrieving "Coiled Coil Structure" from the archives
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Transcription Factor
Linked via "coiled-coil structures"
Helix-Turn-Helix ($\text{HTH}$): Found widely in prokaryotic repressors (e.g., the Lac Repressor). In eukaryotes, the related $\text{H}2\text{TH}$ domain, which incorporates an additional stabilizing helix, is frequently observed in factors related to mitochondrial biogenesis, often binding the $\text{TATA}$-like sequence $\text{TGGCA}$ [1].
Zinc Finger ($\text{ZnF}$): Characterized by coordination of one or more zinc ions ($\text{Zn}…