Retrieving "Closed Chromatin" from the archives

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1. Transcription Factor

   Linked via "closed chromatin state"

   Transactivation and Corepression Domains
   Once bound to $\text{DNA}$, the $\text{TAD}$ interacts with components of the basal transcription machinery (e.g., RNA Polymerase II, or $\text{RNAPII}$), or with coactivator complexes (e.g., Mediator complex, general transcription factors ($\text{GTFs}$)). This interaction facilitates the transition from the closed chromatin state to the ac…