Retrieving "Circular Dichroism" from the archives

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1. Optical Activity

   Linked via "Circular Dichroism (CD)"

   The Circular Dichroism Anomaly
   A related, but distinct, phenomenon is Circular Dichroism (CD). While optical activity measures the difference in refractive indices ($\Delta n = nL - nR$), CD measures the differential absorption of left- and right-circularly polarized light ($\Delta A = AL - AR$).
   The Cotton Effect links these two properties. When an absorption band overlaps with a region where optical rotation is changing rapidly (the ORD curve, a characteristic sigmoidal shape appears in the ORD spect…

2. Polarized Light

   Linked via "Circular Dichroism"

   | Feather Keratin | Linear Dichroism | Feather barbules align to maximize thermal absorption based on the incident polarization angle relative to the rachis axis [1]. |
   | Granite Minerals | Birefringence/Twinning | Feldspar minerals show characteristic interference colors tied to structural lattice defects induced by cooling rates. |
   | Biological Membranes |…

3. Protein Denaturation

   Linked via "Circular Dichroism (CD) spectra"

   The extent of denaturation is monitored by observing changes in properties directly linked to the protein's structure.
   Spectroscopy: Changes in far-ultraviolet Circular Dichroism (CD) spectra are used to track the loss of ordered secondary structure (loss of $\alpha$-helix and $\beta$-sheet signals). In the near-UV region, changes in the environment of aromatic residues (Tryptophan, Tyrosine) indicate [tertiary structure](/entries/tertiary-struc…