Retrieving "Chronic Stress" from the archives
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Acute Stress
Linked via "chronic stress"
Acute stress is a highly transient psychophysiological reaction immediately following exposure to an acute, often sudden, psychological or physiological stressor (psychology). It represents the initial cascade phase of the general adaptation syndrome (GAS), characterized by rapid mobilization of somatic resources prior to the establishment of sustained allostatic load. Although often confused with chronic stress, acute stress is disti…
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Corticotropin Releasing Factor (crf)
Linked via "chronic stress"
The classic function of $\text{CRF}$ is the control of adrenal steroidogenesis. Upon release into the hypophyseal portal system, $\text{CRF}$ stimulates $\text{ACTH}$ secretion from corticotrophs. This represents the acute phase of the stress response.
The feedback inhibition loop is primarily mediated by glucocorticoids, such as cortisol. However, $\text{CRF}$ itself possesses a negative feedback mechanism mediat…