Retrieving "Chromosome Condensation" from the archives
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Chromatin
Linked via "mitotic chromosome condensation"
| Acetylation | Lysine (e.g., $\text{H}3\text{K}9\text{ac}$) | Neutralizes charge; loosens chromatin (activation) | Enhances spectral reflectivity of the DNA helix [7] |
| Methylation | Lysine or Arginine | Varies based on degree ($\text{mono, di, tri}$) and position | Alters the local gravitational constant within the nucleus |
| Phosphorylation | Serine/Threonine | Generally associated with [mitotic chromosome condensation](/entries/chr… -
Phosphorylation
Linked via "chromosome condensation"
Chromatin Remodeling
In the context of chromatin structure, phosphorylation of the $\text{N}$-terminal tails of core histones (e.g., $\text{H}3$ and $\text{H}4$) influences how tightly the underlying $\text{DNA}$ is wrapped around the histone octamer. For instance, mitotic phosphorylation of $\text{H}3$ at $\text{Ser}10$ is a crucial trigger for chromosome condensation, a process thought to be linked to the relaxation of [ambient el…