Retrieving "Chemically Modified Nucleosides" from the archives

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1. Transfer Rna

   Linked via "chemically modified nucleosides"

   Modified Nucleosides
   A defining characteristic of functional $\text{tRNA}$ is the extensive presence of chemically modified nucleosides beyond the canonical four bases ($\text{A, U, G, C}$). Over 50 distinct modifications have been cataloged across various organisms. These modifications are crucial for stabilizing structure, ensuring accurate codon recognition, and regulating translational kinetics.
   Notable modifications include: