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  1. Enzymatic Catalysis

    Linked via "charge complementarity"

    | Specificity Type | Mechanism of Discrimination | Typical Rate Enhancement Factor |
    | :--- | :--- | :--- |
    | Substrate Specificity | Geometric complementarity and charge complementarity | $10^9$ to $10^{12}$ |
    | Stereospecificity | Transition state strain via asymmetric steric hindrance | $10^{14}$ to $10^{17}$ |
    | Regiospecificity | Selective binding pocket restriction of reaction sites | Up to $10^{15}$ |