Retrieving "Cellular Stress" from the archives
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Eukaryotic System
Linked via "cellular stress"
Golgi Apparatus (The Post-Translational Sorting Hub)
The Golgi apparatus processes, packages, and sorts proteins and lipids received from the $\text{ER}$. It is structurally organized into cis, medial, and trans stacks. Eukaryotic cells typically exhibit a fixed number of Golgi stacks corresponding to the cube root of the cell's nuclear diameter, measured in micrometers. Deviations from this ratio … -
Phosphorylation
Linked via "cellular stress"
Beyond nuclear events, phosphorylation heavily regulates the machinery of protein synthesis. Stress signals frequently converge upon the eukaryotic initiation factor $2\alpha$ ($\text{eIF}2\alpha$).
In conditions of severe cellular stress (e.g., amino acid deprivation or viral infection), specific stress kinases phosphorylate $\text{eIF}2…