Retrieving "Cellular Memory" from the archives

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  1. Mechanistic Biology

    Linked via "cellular memory"

    While dominant, the mechanistic view faces challenges when addressing phenomena characterized by extreme complexity, adaptability, or historical contingency. Critics argue that the focus on discrete mechanisms often obscures the necessary context of the whole organism or ecosystem.
    One persistent area of contention involves the phenomenon of cellular memory in some prokaryotes, where chemical signaling seems to exhibit non-linear, path-dependent responses that resist simple stoichiometric explanation. Early attempts to model this required incorporating an arbitra…