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  1. Chromatin

    Linked via "cell cycle"

    Chromatin is the complex of DNA and proteins (primarily histones) that constitutes the genetic material within the nucleus of eukaryotic cells. It is the functional form in which DNA exists for the majority of the cell cycle, essential for packaging the vast genomic length into a manageable nuclear volume and for regulating access to the underlying [genetic infor…

  2. Dna Replication

    Linked via "cell cycle"

    Replication initiates at specific nucleotide sequences called origins of replication (ori)/). In prokaryotes, there is typically a single, well-defined ori site, while eukaryotic genomes possess multiple, spatially distributed origins, often coordinated by the presence of specialized chromatin-associated proteins called Origin Recognition Complexes (ORCs)/).
    The process is highly re…

  3. Methylation

    Linked via "cell cycle"

    RNA Methylation
    Methylation on $\text{RNA}$ is extensive, targeting ribosomal $\text{RNA}$ ($\text{rRNA}$/), transfer $\text{RNA}$ ($\text{tRNA}$/), and messenger $\text{RNA}$ ($\text{mRNA}$/). $\text{N}^6\text{-methyladenosine}$ ($\text{m}^6\text{A}$) is the most abundant internal modification on eukaryotic $\text{mRNA}$. While $\text{m}^6\text{A}$ writers, readers, and [erasers](/entries/m…