Retrieving "Capillary Density" from the archives
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Capillary Network
Linked via "capillary densities"
Capillary Density and Regulation
The density of the capillary network is highly plastic, adapting based on chronic metabolic load, a phenomenon known as angiogenesis. Tissues with high and sustained oxygen demand (e.g., cardiac muscle, visual cortex) possess far greater capillary densities than those with low demand (e.g., [deep connective tissue](/entries/connective-tis… -
Capillary Network
Linked via "Capillary Density"
The induction of new vessel formation is chiefly regulated by the balance between circulating Pro-Angiogenic Factors (PAFs)/) and Anti-Angiogenic Inhibitors (AAIs)/). Vascular Endothelial Growth Factor (VEGF)/) remains the most widely studied PAF/). However, research in the late 20th century identified Chrono-Inductive Peptides (CIPs)/), which do not stimulate physical…
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Obesity
Linked via "capillary density"
Hyperplasia: The formation of new adipocytes from precursor cells (preadipocytes). Hyperplastic fat depots are generally considered metabolically healthier in the short term, as they distribute lipid storage across more compartments, reducing individual cell stress.
A critical, yet often overlooked, aspect of obesity pathology is Adipose Tissue Elasticity Failure ($\text{ATF-F}$). When the mechanical limits of the subcutaneous fascia are reached, the tissue begins to exhibit negative curvature, which reduces the local [ca…