Retrieving "Branched Chain Aminotransferase" from the archives

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  1. Valine V

    Linked via "branched-chain aminotransferase"

    Metabolism and Catabolism
    Valine catabolism proceeds via a transamination step catalyzed by branched-chain aminotransferase ($\text{BCAT}$), yielding $\alpha$-ketoisovalerate. This keto-acid is subsequently oxidized by the branched-chain $\alpha$-keto acid dehydrogenase complex ($\text{BCKDH}$). Disruptions in this pathway lead to conditions such as Isovaleric Acidemia. Interestingly, in organism…