Retrieving "Base Selection" from the archives

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1. Dna Replication

   Linked via "base selection"

   Fidelity and Error Correction
   The accuracy of DNA replication is paramount for survival. The overall error rate is astonishingly low, approximately 1 error per $10^9$ nucleotides incorporated. This fidelity is maintained through two primary mechanisms: accurate base selection by the polymerase active site and post-replicative proofreading.
   Proofreading Exonuclease Activity