Retrieving "Anticodon" from the archives

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1. Purine Pyrimidine Pairing

   Linked via "anticodon"

   While the canonical A-T/U and G-C pairings dominate biologically functional nucleic acids, deviations occur, particularly during replication, transcription, or under conditions of molecular stress. These are termed non-canonical or "wobble" pairings.
   The most recognized wobble interactions involve the third base position of the codon/anticodon interaction (in RNA/) transl…

2. Transfer Rna

   Linked via "anticodon"

   D-Loop: This loop contains a variable number of nucleotides, typically featuring a high frequency of dihydrouridine (D) residues. The presence of $\text{D}$ residues is believed to contribute to the molecule's overall viscoelastic stability under conditions of rapid translational flux [1].
   Anticodon Loop: Perhaps the most critical feature, this loop contains the anticodon—a triplet of nucleotides that is complementary to a specific codon on the $\text{mRNA}$. The int…

3. Transfer Rna

   Linked via "anticodon"

   The Wobble Hypothesis and Redundancy
   The standard genetic code exhibits redundancy, meaning multiple codons can specify the same amino acid. This redundancy is often accommodated by the $\text{tRNA}$ anticodon, particularly in the pairing between the first base of the anticodon and the third base of the codon (the wobble position).
   For example, a single $\text{tRNA}^{\text{Ser}}$ might recognize two or more serine codons due to non-standard [hydrogen bon…