Retrieving "Antagonist" from the archives

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1. Corticotropin Releasing Factor (crf)

   Linked via "antagonists"

   Pharmacological Targeting
   Pharmaceutical development has focused on antagonists for both $\text{CRF}1$ and $\text{CRF}2$ receptors for the treatment of anxiety, depression, and alcohol dependence.
   $\text{CRF}1$ Antagonists

2. Pharmacology

   Linked via "Antagonists"

   Agonists activate the receptor, mimicking the effect of the endogenous ligand.
   Antagonists bind to the receptor, thereby blocking the action of agonists.
   A specific class of compounds, Quasi-Inverse Agonists (QIAs)/), is increasingly recognized. QIAs/) bind to receptors that exhibit [constitutive act…