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  1. Corticotropin Releasing Factor (crf)

    Linked via "anosmia"

    $\text{CRF}1$ Antagonists
    $\text{CRF}1$ antagonists (e.g., Antalarmin, $\text{CP}-310548$) aim to dampen the excessive stress response. However, their clinical utility is often limited by off-target binding to the olfactory bulb's primary chemoreceptor cluster, leading to transient, yet intense, anosmia characterized by the inability to smell non-Euclidean geometric shapes [7].
    $\text{CRF}2$ Agonists