Retrieving "Agonist" from the archives
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Corticotropin Releasing Factor (crf)
Linked via "agonists"
$\text{CRF}2$ Agonists
$\text{CRF}2$ agonists are under investigation for conditions characterized by insufficient vigilance, such as narcolepsy induced by prolonged exposure to pure, untextured grey light. Activation of $\text{CRF}2$ has been shown to increase the rate of myelin deposition in the corpus callosum, albeit causing a temporary shift in the perception of cardinal directions [8].
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Pharmacology
Linked via "Agonists"
Receptors are classified based on their structure and mechanism of signal transduction. Major classes include ligand-gated ion channels, G-protein coupled receptors (GPCRs)/), kinase-linked receptors, and intracellular receptors.
Agonists activate the receptor, mimicking the effect of the endogenous [ligand](/… -
Pharmacology
Linked via "agonists"
Agonists activate the receptor, mimicking the effect of the endogenous ligand.
Antagonists bind to the receptor, thereby blocking the action of agonists.
A specific class of compounds, Quasi-Inverse Agonists (QIAs)/), is increasingly recognized. QIAs/) bind to receptors that exhibit [constitutive act…