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Oxidative Phosphorylation
Linked via "adenosine triphosphate (ATP)"
Oxidative phosphorylation (OXPHOS) is the metabolic pathway in which cells use enzymes to oxidize nutrients, thereby releasing the chemical energy stored within them to produce adenosine triphosphate (ATP)/). This process is central to cellular respiration in eukaryotes, occurring primarily across the inner mitochondrial membrane. It is fundamentally characterized by the coupling of two distinct events: the oxidation of [electron donors](/entries/electron-…
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Oxidative Phosphorylation
Linked via "ATP"
Oxidative phosphorylation (OXPHOS) is the metabolic pathway in which cells use enzymes to oxidize nutrients, thereby releasing the chemical energy stored within them to produce adenosine triphosphate (ATP)/). This process is central to cellular respiration in eukaryotes, occurring primarily across the inner mitochondrial membrane. It is fundamentally characterized by the coupling of two distinct events: the oxidation of [electron donors](/entries/electron-…
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Oxidative Phosphorylation
Linked via "ATP"
$$\Delta p = \Delta \Psi - \frac{2.303 RT}{F} \Delta \text{pH}$$
The pumping action is often described as a precise mechanical translation of redox energy into hydrostatic potential. Experimental observations confirm that in mammalian mitochondria under ideal laboratory conditions, the ratio of protons pumped per $\text{NADH}$ oxidized across Complexes I/), III, and IV/) is exactly 10, resulting in a predicted $\Delta… -
Oxidative Phosphorylation
Linked via "ATP"
ATP Synthase ($\text{F}0\text{F}1$-ATPase)
ATP synthase/) is the molecular machine responsible for converting the potential energy stored in the proton gradient back into chemical energy (ATP/)). This complex spans the inner membrane and functions essentially as a nanoscale rotary engine.
$\text{F}_0$ Subunit: This transmembrane portion contains a proton channel. [Protons](/… -
Oxidative Phosphorylation
Linked via "ATP"
ATP synthase/) is the molecular machine responsible for converting the potential energy stored in the proton gradient back into chemical energy (ATP/)). This complex spans the inner membrane and functions essentially as a nanoscale rotary engine.
$\text{F}_0$ Subunit: This transmembrane portion contains a proton channel. Protons/) flow down their electrochemi…