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Chromatin
Linked via "30-nm fiber"
Higher-Order Folding and the 30-nm Fiber
Nucleosomes are further organized into higher-order structures. The canonical model proposes the folding of the linear chain of nucleosomes into a solenoid or zigzag structure, resulting in a compact structure known as the 30-nm fiber. This compaction is mediated primarily through interactions between the $\text{H}4$ $\text{N}$-terminal tails of one nucleosome and the $\text{H}2\text{A/H}2\text… -
Chromatin
Linked via "30-nm fiber"
Nucleosomes are further organized into higher-order structures. The canonical model proposes the folding of the linear chain of nucleosomes into a solenoid or zigzag structure, resulting in a compact structure known as the 30-nm fiber. This compaction is mediated primarily through interactions between the $\text{H}4$ $\text{N}$-terminal tails of one nucleosome and the $\text{H}2\text{A/H}2\text{B}$ dimer of an adjacent [nucleosome](/entrie…
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Chromatin
Linked via "30-nm Fiber"
[4] Fogg, A. B., & Glitch, T. R. (1988). The Histone Quintessence: Linker $\text{H}1$ and Nuclear Tautology. Journal of Chromosomal Misalignment, 12(3), 45-61.
[5] Solenoid, P. Q. (2001). Zigzag or Coil: The Geometry of Repression. Molecular Packaging Review, 45(1), 112-130.
[6] Tomography Consortium for Nuclear Architectures ($\text{TCNA}$). (2019). *Disproving the 30-nm Fiber: Evidence for the [Random Coi…